1+ months

Senior Scientist, Immunology (Immunosafety Sciences)

Groton, CT 06340
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Pfizer colleagues have many perspectives, backgrounds, and strengths, but we share one goal: to improve the lives of patients. Immunosafety Sciences is a global resource within Drug Safety Research & Development (DSRD) focused on supporting drug development across all therapeutic areas. Activities include assay development and sample testing for non-clinical and clinical studies in the areas of immunomodulation, immuno-oncology and hypersensitivity. Immunosafety Sciences is also involved in the risk assessment process, regulatory filings, and investigative studies to understand immune-related safety issues during all stages of drug discovery.

We're excited to present a Senior Scientist, Immunosafety Sciences open position. The successful candidate will be a highly motivated scientist with a solid background in molecular immunology and both cellular and plate-based immunological assays. The candidate will work in a team environment and will focus on the conduct of immunological assays in support of drug development and strategic initiatives, in both nonclinical and clinical arenas. The candidate will explore state-of the-art technologies particularly in the areas of molecular immune profiling, scRNAseq and TCR sequencing, and contribute data for publishing in peer-reviewed journals. This person will effectively work on several projects at a time and interact with staff from other departments.

At Pfizer, we believe in helping people lead healthier lives - from our customers to our colleagues. We offer a wide array of programs and plans that give our colleagues the flexibility and tools they need to get and stay healthy, both physically and financially. These include competitive compensation, generous medical, vacation and retirement benefits as well as a number of additional programs. The Immunosafety Sciences Group offers a collegial and supportive environment for colleagues, with a culture encouraging openness, innovation and ownership of our science. We aim to provide scientific and growth opportunities for personal and career development commensurate with a colleague's goals and experience.


+ Responsible for evaluating cutting edge methods to investigate immune cell phenotypes and immunologic signatures.

+ Responsible for conducting experiments in molecular biology, e.g. PCR, RNA seq.

+ Train other users on all aspects of molecular biology especially experimental planning, data acquisition and analysis.

+ Accountable for the conduct of immunoassays; ELISA, electrochemiluminescent assays, or other assay platforms, and cell-based assays (e.g., proliferation, cytotoxicity, receptor binding, phagocytosis, ADCC [Antibody-dependent cell-mediated cytotoxicity]).

+ Will perform experiments involving ELISpot, flow cytometry, and cell culture techniques.

+ Will apply strong problem-solving and trouble-shooting skills to experimental evaluations.

+ Responsible for interpreting data, working independently and collaborating across lines.

+ Responsible for the interpretation and summarization of experimental data and reports in team meetings.

+ Responsible for maintaining laboratory notebooks, preparing project plans, generating reports, and presenting project plans and data to teams.


+ MA/MS with 7+, or PhD with 0-2 years of experience in molecular immunology and a degree in immunology, molecular biology, or related biological science.

+ Experience supporting multi-disciplinary project teams including generating high quality data in a time-sensitive fashion.

+ Record of peer-reviewed publications


+ Education and practical training in the area of molecular immunology are highly desirable. Current knowledge of single cell RNA sequencing methodologies and TCR sequencing, and application of computational methods for the analysis of molecular and cellular pathway data.

+ Expertise with mechanistic investigation of toxicity findings.

+ Expertise in ELISpot and flow cytometry highly desired.

**Other Job Details:**

+ Eligible for Employee Referral Bonus


**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development
Posted: 2020-01-29 Expires: 2020-08-06
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Senior Scientist, Immunology (Immunosafety Sciences)

Groton, CT 06340

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