1+ months

Senior Principal Scientist, Cytokine Biology I

La Jolla, CA 92037
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Pfizer Cancer Immunology Discovery (CID) is within the Oncology division of Pfizer Worldwide Research & Development in La Jolla, CA. CID is dedicated to developing new protein therapeutics to improve human life by redirecting the immune system against cancer. CID researchers apply the latest scientific knowledge and novel approaches to discover truly innovative Immuno-Oncology therapeutics.


Lead mechanistic/investigational efforts to discover and develop new therapeutic modalities for cancer immunotherapy focusing on cytokines as targets

Independently design and perform studies to evaluate mechanism of action and preclinical biomarkers for CID's preclinical-stage cytokine therapeutics

Develop and test combination strategies for cytokine therapeutics

Independently generate high quality laboratory-based investigative data to support project progression and clinical indications

Mentor and cross-train other scientists within Cancer Immunology Discovery

Collaborate with protein engineering, computational biology, and clinical development group to pursue the most promising drug candidates through clinical trials

Communicates experimental findings accurately and concisely in both oral and written formats; analyzes, documents and reports laboratory data in accordance with company standards and procedures.

Lead collaborations with internal and external collaborators

Present at group meetings, global project team meetings, and site meetings


Ph.D. with 8+ years of experience (prefer 8+ years post-Ph.D.)

Demonstrated expertise in the field of immunology, cell biology and/or genetics

Solid technical knowledge and hands-on experience with conventional immunological techniques. Broad experience in assessing immune cell function. Experience in immune cell isolation and characterization using multi-color flow cytometry.

Working knowledge of various murine tumor and/or infectious disease models

Ability to independently design, plan and execute and interpret experiments

Ability to manage an independent research program with no supervision

Ability to organize and communicate complex data sets in a clear and concise manner to key stakeholders from diverse backgrounds

Ability to lead a scientific team responsible for immunological drug discovery research programs, including identification and validation of novel targets, mechanism of action and preclinical biomarkers

Ability to represent development teams and communicate goals/deliverables to senior management and/or governance committees

Prior experience working with or leading collaborations with external academic, biotechnology, and contract research organizations

Experience in mentoring and/or leading Ph.D. level and non-Ph.D. level scientists

Excellent organization and planning skills, the ability to work in a fast-paced environment independently or as part of a team, good verbal and written communication, and strong motivation with a dedicated work ethic


8+ years post-Ph.D. and 4+ years industrial experience

**Other Job Details**

+ Eligible for Relocation Package

+ Eligible for Employee Referral Bonus

**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.


N (Other) (United States of America)

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
Posted: 2019-07-17 Expires: 2019-10-17

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Senior Principal Scientist, Cytokine Biology I

La Jolla, CA 92037

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