1+ months

Senior Director, Global Medical Impact Assessment Senior Decision Scientist

New York, NY 10007
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The Global Medical Impact Assessment (GMIA) group is an internal quantitative decision science service function within Pfizer's Worldwide Medical and Safety (WMS) organization, that works closely with RU/BU/Medical Affairs/Functional Areas to thoroughly understand the clinical value of medicines for patients & providers that informs regulatory/business priorities, opportunities and challenges using quantitative decision science methods. They will work with portfolio/functional teams to develop a quantitative decision support strategy that is specific to the portfolio and aligns with model informed drug development. They will design and execute multi-attribute analyses in collaboration with partner functions and external partners. They will significantly increase Pfizer's external scientific contribution to decision science with regulatory & HTA policy makers. More specifically, they will:

+ Be aligned across business unit/therapeutic areas and become a strategic partner for product development, launch, and extensions

+ Identify strategic opportunities, innovative solutions and develop business cases that increase clinical value of pipeline & in-line medicines to regulatory & HTA decision makers by leveraging quantitative multi-attribute analyses and preference data

+ Partner with regulatory and policy colleagues to advance regulatory & HTA acceptance of quantitative decision methods by leading external scientific narrative & initiatives

+ Partner with key opinion leaders to drive breakthroughs in operational and strategic quantitative decision excellence by accelerating decision science innovation

+ Partner closely with colleagues in Research, Safety, Clinical, Real World Evidence and Patient Health Impact, etc. to better inform governance, regulatory and HTA decision makers by applying quantitative decision methods

+ Increase agile, responsive, cross-functional asset team decision making to reduce R&D cycle time by driving operational excellence in clinical value assessment

Pfizer is excited to present a Senior Director, Global Medical Impact Assessment Senior Decision Scientist opening in our group. The ideal candidate should have extensive experience in decision science, multi-attribute analyses applied to healthcare, have capability to implement alternative approaches and work collaboratively with other strategists, experienced utilizing multi-sourced clinical, real-world and preference data, gain acceptability for methods, and defend benefit-risk and clinical value justifications to experts, regulatory and health authorities. Reporting directly to the Head of Global Medical Impact Assessment group, this highly visible role requires someone with strong strategic thinking, leadership, communication and people management skills.



+ Establishes credibility/trust and advises/pilots with Regulators /Health Authorities to negotiate standardize decision science solutions by problem type and achieve success by defending methods, pathways, product benefit/risk and clinical value analyses

+ Responsible for the development and implementation of RU/BU/WMS level strategic plan with interfaces to governance structures for empowered, agile, responsive medical decision making (e.g. Model Informed Drug Development)

+ Build effective working relationships with RU/BU/ WMS leads and Medical Affairs Team Leads to ensure stakeholder requirements are addressed

+ Builds relationship, align, and negotiate with portfolio teams, RU/BU/Medical Affairs, Regional, and Corporate leaders and internal/external stakeholders for agreement on decisions, justifications, alternative pathways, policies, and processes

+ Manages GMIA interface with study management, operations, statistics, clinical, and finance

+ Develops overall prospective strategy to advance methods and technology for quantitative clinical decision making

+ Ensures awareness by appropriate functional groups of GMIA deliverables and timelines (e.g., QA/QC, Regulatory, QPPV)

+ Provide expert consultation on all aspects of quantitative clinical decision analysis including objectives, study design, data source curation, analysis plan development, statistical analysis, and/or interpretation

+ Forms strong partnerships with business units, medical affairs, market access, and HEOR teams in understanding multi-attribute analysis needs and priorities, and develops plans to execute GMIA projects based on those needs;

+ Acts as a Liaison for the Global Medical Impact Assessment group across Pfizer

+ Contribute to the development and implementation of an enterprise GMIA strategy at Pfizer


+ Lead, mentor, support, and provide direct line management to team members or contractors

+ Lead, mentor, support, and provide direction to designers and strategists about GMIA-accountable areas of expertise


+ Proposes, develops and leads/oversees key cross- functional strategic initiatives

+ Determines and aligns decision-makers on portfolio-wide decision science needs, strategy, and opportunities for alternative pathways

+ Lead teams across the project lifecycle from requirements gathering, multi-source data curation, hypothesis generation, ideation, coding, testing, and deployment of decision science product

+ Develop a deep understanding of the decision needs and ensure delivery of GMIA programs that are responsive and strongly supportive of the end-to-end value evidence strategy

+ Ensure high quality, readily interpretable deliverables (e.g. effects tables, graphs, clinical utilities, study reports) are generated from GMIA studies/analyses

+ Understand clinical decision needs for key disease areas and ensure appropriate methods, analytics, or data sources are utilized and responsible for ensuring inspection readiness and business/regulatory compliance

+ Leads knowledge center and operational continuity for disease-area focused content, issues and represents these to customers, collaborators, and external parties (regulatory authorities, opinion leaders, academia, investigators, etc.)


+ Reviews and approves analyses deliverables for development and product teams using established systems within WMS for maintaining quality

+ Responsible for resource allocation decisions and sharing resource for support across the portfolio

+ Reviews and approves quantitative deliverables for, research, development and product teams using established systems within WMS for maintaining quality

+ Advises, manages, and trains team members to deliver projects on time, with quality, efficiently, and effectively



+ Contribute to the continuing education of relevant line functions on the use of quantitative decision science methods

+ Develops and implements strategic communication plan to educate Pfizer stakeholders of the value, opportunities, data, methods, analytics, and processes to implement alternative pathways and analyses

+ Ensures awareness and adoption of GMIA shared services capabilities by appropriate functional groups within Pfizer


+ Partner with regulatory and policy colleagues to advance regulatory & HTA acceptance of quantitative decision methods by leading external scientific narrative & initiatives

+ Partner with key opinion leaders to drive breakthroughs in operational and strategic quantitative decision excellence by accelerating decision science innovation

+ Influences the external environment as a public spokesperson and demonstrated leader (e.g., leadership and membership in PhRMA, ISPE or other scientific bodies, scientific presentations and publications)

+ Publication and presentation of GMIA projects at internal meetings, and external industry conference/workshops

+ Develop effective relationships with external thought leaders in decision science, comparative effectiveness research, health informatics, and data sciences so as to maintain an extensive understanding of external environment, to create opportunities for engagement, and to establish Pfizer as a leader in the field.



+ PhD, MD, or PharmD and 12+ years of experience in Decision Science, Bioinformatics, Clinical Science, Epidemiology, Quantitative Public Health discipline, or related discipline

+ Extensive track record applying multi-attribute analytic methods to clinical research and clinical value assessment

+ Experience with clinical, observational. real-world evidence and preference data synthesis

+ Demonstrated depth of understanding of observational research methods, HTA, comparative effectiveness research, health care and data science trends, and ability to leverage health outcomes and data science expertise to meet evolving business needs

+ Evidence of technical expertise of applying multi-attribute analyses to evidence and insights generation at a therapy/product level

+ Understanding client challenges and soliciting support for new opportunities to build project portfolio

+ Interpersonal skills to interact on both business and scientific issues along with negotiation and facilitation skills to align group decisions

+ Experienced in managing meetings / projects / team members

+ Creative skills in designing alternative approaches, new solutions, or innovations

+ Ability to identify common operational trends and to standardize and optimize processes for ease of implementation

+ Extensive expertise in decision science & multi-attribute analyses to advise, on disease areas, data, technology, and product benefit-risk management strategies

+ Previous successful pilots and publications with alternative rationales

+ Ability to explain strengths and limitations of quantitative decision science analyses with multisource datasets - multicriteria decision analysis (MCDA), stochastic multicriteria acceptability analysis (SMAA),- in context of regulatory and HTA review.

+ **Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve** **meaningful outcomes and create business impact**


+ Preference for 5 or more years' experience in the pharmaceutical industry; track record interacting with R&D and commercial organizations in pharmaceutical industry

+ Established credibility / trust with Regulatory Agencies

+ Previous successful pilots with alternative rationale

+ Proven success defending methods/ product with regulators

+ Extensive expertise in quantitative decision science

+ Stakeholder negotiation/defense

+ SME Operational Continuity

+ Respected advisor / trusted aligner across stakeholders

+ Excels in leading multi-functional teams to customize portfolio-wide evidence-based strategies

+ Extensive expertise aligning decision-makers in alternative directions prospectively

+ Experienced leader with demonstrated ability to build effective teams and develop talent

+ Able to motivate and channel energy of others toward a clear purpose

+ Demonstrated ability to develop and maintain strong relationships with external customers and experts

+ Well-developed business acumen, demonstrated customer focus and strong decision-making skills

+ Excellent matrix, interpersonal and influencing skills

+ Financial management experience

+ Experience in leading and managing change, including a track record of flexible, out-of-the-box thinking and responding effectively to rapidly changing requirements

+ Excellent verbal and written communications skills

+ Enlists others to align objectives with those of the organization

+ Demonstrates evidence of strategic thinking and can effectively communicate the impact of proposed plans and actions

+ Strong desire to reach challenging goals and continuously improve

+ Works tenaciously through difficulties to achieve best results.


10-25% travel may be required to meet with external stakeholders or regional team members

**Other Job Details:**

+ Additional Location Information: New York, NY; Collegeville, PA; Groton, CT

+ Eligible for Employee Referral Bonus


**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Posted: 2020-02-24 Expires: 2020-04-25

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Senior Director, Global Medical Impact Assessment Senior Decision Scientist

New York, NY 10007

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