1+ months

Principal Scientist

Pearl River, NY 10965
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The incumbent will direct a team dedicated to the generation of antibodies as tool reagents for antigen and/or vaccine candidate characterization as well as for development of clinical testing assays. The incumbent will be responsible for leadership and strategic direction for the generation and development of different types of antibodies with a focus on monoclonal antibodies originated by hybridoma fusion with respective evaluation of functional activity. Team responsibilities include screening, expression, purification and characterization of monoclonal antibodies with various bioanalytical methodologies and functional assays.

As a leader, the incumbent will work cross-functionally and in a matrix environment with other research and development groups and participate as SME on multiple teams.

The ability to work in teams, write reports, standard operation procedures (SOPs) and publications for peer review is expected.


+ Lead a team of dedicated junior scientist in the generation and characterization of monoclonal antibodies

+ Interface with other groups/project teams (internal, external, customers, CROs) to identify need for monoclonal reagents and define timelines and scheduling to meet project goals

+ Capability to multitask various projects and their priorities is expected along with excellent problem solving skills in the planning and execution of objectives.

+ Interpret, summarize and present experimental data, including at group, project level and departmental meetings

+ Participate in the evaluation of new methods and technologies.

+ Prepare research reports and contribute to primary publications.

+ Train junior Scientists and coleagues cross-functionally

+ Maintain laboratory notebook in a detailed and descriptive manner.


Ph.D. with 5 years postdoctoral experience, preferably with at least 3 years in an industrial setting (i.e. within the antibody, molecular biology and/or immunology area).

Experience in hybridoma technology including hands-on-skills in the performance of fusions as well as generation of monoclonal antibodies in mice and rabbits.

Experience in cell culture work with various mammalian cells.

Knowledge of antibody purification with state-of-the-art technologies such as different chromatography methods (affinity, ion-exchange).

Hands-on skills in protein analytics such as ELISA, immune blot, Octet/Biacore, neutralization assays and/or Flow cytometry (FACS).

Skills to write SOPs, reports, scientific papers and supporting drafts for patent applications independently; as well as to present scientific data internally and externally at conferences.

Understanding of relevant work from the scientific community and using the information to improve internal processes and/or establish new procedures/technologies.

Experience in leading teams.


The candidate must possess excellent verbal and written communication skills.

Proficiency with Microsoft Office applications and relevant scientific software, including bioinformatics and graphing/statistical analysis tools is expected.

Experience with database systems such as LIMS to maintain antibody inventor.

**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

**Other Job Details:**

+ Additional Location Information: Pearl River, NYEligible for Employee Referral Bonus

+ Eligible for Relocation Package

N (Other) (United States of America)

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
Posted: 2019-07-10 Expires: 2019-11-14

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Principal Scientist

Pearl River, NY 10965

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