23 days old

Computational Scientist, Machine Learning

Cambridge, MA 02139
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Pfizer Simulation and Modeling Sciences (SMS) group has an opening for a computational methods developer with expertise in molecular modeling, machine learning (ML), and scientific programming. The successful candidate will develop and deploy molecular modeling techniques, ML models, and computational tools to support mRNA based therapeutic efforts across Pfizer.


+ In collaboration with key stakeholders across Pfizer R&D, develop state-of-the-art molecular modeling techniques, ML models, and computational tools to support mRNA therapeutics efforts. Specific tasks include, but not limited to, development of computational approaches to predict mRNA degradation and methods to improve their stability through efficient sequence optimization.

+ Leverage proprietary computational framework and applications to deploy computational methods and ML models for wide usage by Pfizer scientists.

+ Occasionally contribute to the ongoing and new method development efforts within SMS focusing on small molecule and biotherapeutics lines.

+ Proactively identify, assess, and internalize promising methods and tools from external publications.

+ Communicate and explain computational models and ML algorithms to broad scientific audience from diverse discipline.


+ Ph.D. in computational chemistry, physical or biological sciences, chemical engineering, computer science, or related discipline.

+ Proficiency in general molecular modeling techniques.

+ Proficiency in high-level programming language (e.g. Python); experience with Unix/Linux, HPC environments.

+ Experience with machine learning.

+ Strong track record of publications demonstrating applications of molecular modeling and/or ML to problems of pharmaceutical interest.

+ Excellent communication and interpersonal skills.


+ Experience in applying molecular modeling and/or ML to mRNA design and optimization.

**Additional Job Information:**

+ Eligible for employee referral bonus

+ Eligible for relocation support


**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Information & Business Tech
Posted: 2021-05-28 Expires: 2021-06-28
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Computational Scientist, Machine Learning

Cambridge, MA 02139

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