1+ months

Associate Scientist, Upstream Process Development

St Louis, MO 63103
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An Associate Scientist (R1) position is available in the Process Development group of Bioprocess R&D. The successful applicant will join a team of scientists and engineers focused on developing and optimizing microbial/ mammalian cell culture processes for recombinant proteins and biologics for early- and late-phase clinical trials. In this role you will be responsible for designing and executing bioreactor experiments in bench-top bioreactors and associated scale-down equipment with the goal of developing robust, scalable, and high productivity processes that produce therapeutic proteins with the appropriate product quality to treat human disease. The work will also involve working with pilot scale, commercial and clinical production facilities to ensure accurate technology transfer and successful large-scale production. You may also be involved in cutting edge technology development projects that seek to discover broadly applicable methods to intensify microbial or mammalian cell culture.


+ Execute fermentation/ cell culture experiments in automated bioreactors

+ Perform relevant analytical methods

+ Analyze and communicate experimental results both orally and in writing

+ Represent the upstream process development function within cross-functional teams

+ Transfer upstream process technology to pilot plant and GMP manufacturing facilities


+ BS/BA in Biotechnology, Microbiology, Cell Biology, Chemical Engineering, Biochemistry or equivalent.

+ Requires competency in aseptic laboratory technique and the ability to design complex experiments and interpret data.

+ Requires demonstrated effectiveness in collaborative projects, and ability to communicate effectively with scientists and management in a highly matrixed organization.


+ 0-2 years industrial experience.

+ Knowledge of drug development processes for progression of a biological candidate.

+ Practical knowledge of microbial/ mammalian cell culture and cell physiology

+ Practical knowledge of cell expression systems

+ Experience developing commercially relevant processes to produce pharmacologically active proteins

+ Experience in supporting the scale-up and technology transfer to pilot/commercial scales

+ Knowledge of GLP/GMP practices

+ Excellent oral and written communication skills

+ Extreme attention to detail

+ Experience with technical report writing


Position requires occasional light lifting and periods of standing, sitting or walking. Some regular air travel required.


Occasional weekend work required


**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Eligible for Employee Referral Bonus: YES

N (Other) (United States of America)

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
Posted: 2019-08-05 Expires: 2019-10-05

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Associate Scientist, Upstream Process Development

St Louis, MO 63103

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