1+ months

Associate Scientist, Glycoconjugates

Pearl River, NY 10965
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The incumbent candidate will participate in the development, scale-up and transfer of manufacturing processes for glycoconjugates . Primary duties include; development of new/novel conjugation methods, analysis of glycoconjugates using colorometric and chromatographic methods, and optimization of process parameters including conjugation and purification. Experience in the prepration of glycoconjugates is highely desired In addition experience with in-process analytical techniques espessially running and interpreting NMR is highly desired. Careful documentation of work and presentation of data is required. All work is to be done in a compliant manner according to SOP guidelines and cGMP/GLP regulations, where applicable.

Conducts all activities and makes decisions that are in accordance with Company policies & SOPs, Pfizer Values, & global regulatory guidelines (including cGMP/cGLP/cGCP), environmental guidelines, as appropriate, etc.


+ Develop of conjugation processes for carbohydrate-protein conjugates

+ In-process analysis (wet chemistry and chromatographic) of glycoconjugates

+ Collaborate with colleagues within Vaccine Research and Development organization including Bioprocess Fermentation, Purification, Analytical, and Formulation Development groups.

+ Present problems and propose solutions in discussions with group members. Offer insights based on experience to group members to help solve existing problems.

+ Author and review purification procedures and reports.

+ Maintain detailed records and keep management informed as to the progress or issues.

+ Keep abreast of scientific/ technological development by participating in scientific meetings/ seminars and through regular scientific review. Utilize new technologies and establish those technologies to improve purification / recovery capabilities of process development group.

+ Perform timely notebook entries and review for completed experiments.

+ Perform other duties as assigned


+ BS in Chemistry, Biotechnology, Engineering or related discipline with 0-3 years of academic, pharmaceutical, or biotechnology postdoctoral experience is necessary.

+ A background in carbohydrare/polymer conjugation and analysis.

+ Experience analyzing carbohydrates, polymers and conjugates.

+ Strong verbal and written communication skills are required.


+ Proficiency with personal computers including word processing, spreadsheets, PowerPoint and relevant scientific software is desirable.


+ Knowledge and ability to independently design, plan, and execute purification / recovery activities. These should also include the ability to operate and maintain relevant instruments, resolve technical problems related to instruments, and execution of analytical / biophysical characterization methods.

+ Proficiency and ability to utilize various techniques such as NMR, FPLC / HPLC, UV-Vis, CD, fluorescence spectroscopy to isolate and, when necessary, characterize purified vaccine candidates.

+ Independently analyze and provide conclusions regarding experimental data generated

**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

**Other Job Details:**

+ Additional Location Information: Pearl River, NY

+ Eligible for Employee Referral Bonus


N (Other) (United States of America)

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
Posted: 2019-07-30 Expires: 2019-09-29

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Associate Scientist, Glycoconjugates

Pearl River, NY 10965

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